When people compare CBD topicals, one of the first things they often notice is the number printed on the front of the container. But milligram strength is only one part of a topical CBD formulation.

With a topical product, the complete formulation matters too. That is one of the reasons the 33 Supply 500mg Liposomal CBD Topical Balm is built around more than CBD strength alone.

What Is the 33 Supply 500mg Liposomal CBD Topical Balm?

The 33 Supply balm is a 2 oz topical product designed for external application. Its product profile includes:

• 500mg total labeled CBD
• Liposomal formulation
• Broad-spectrum hemp-derived CBD
• THC-free profile
• Camphor + peppermint
• Topical delivery method
• Third-party testing information when available

Unlike a tincture, softgel, spray or gummy, this product is designed specifically as a topical. That makes the delivery method and formulation important parts of the product—not simply the milligram number.

Why Formulation Matters

It is easy to compare topical CBD products by looking only at milligram strength. A 1,000mg jar appears stronger than a 500mg jar, for example.

But a topical is a complete formulation. The carrier system, ingredients, concentration and way the product is constructed can all be relevant when evaluating topical delivery.

Research examining topical CBD has shown that the vehicle and formulation can influence CBD skin permeation. Experimental studies have also evaluated lipid- and liposome-based delivery systems as ways of improving the movement of CBD into or through skin compared with certain conventional formulations.

That distinction is important. Our message is not that a 500mg balm should automatically outperform every higher-strength product.

Milligram strength should not be the only factor used to compare topical CBD formulations.

What Does “Liposomal” Mean?

Liposomes are microscopic structures made primarily from lipids. In formulation science, lipid-based systems can be used as carriers for compounds that do not readily mix with water.

CBD is highly lipophilic, meaning it has an affinity for fats and lipids. This is one reason lipid-based delivery systems are an area of interest in topical CBD formulation research.

For the 33 Supply balm, the practical takeaway is straightforward: liposomal formulation is part of the product design—not simply a marketing term attached to the milligram strength.

When comparing topicals, it is useful to consider:

• Milligram strength
• Delivery technology
• Topical formulation
• Ingredient profile
• Extract type
• Available testing documentation

Why Choose a Topical Delivery Method?

CBD products are available through several different delivery methods, and they should not all be evaluated as though they are the same type of product.

• Softgels: pre-measured capsules
• Tinctures: measured liquids
• Sprays: liquid delivered through a spray mechanism
• Gummies: pre-portioned edible products
• Topicals: products designed for external application

The 500mg Liposomal CBD Topical Balm gives customers an externally applied option without measuring a liquid or taking a capsule.

“Which delivery method am I actually looking for?”

What’s Inside the Balm?

Liposomal Formulation

The delivery system is part of what differentiates this balm from a basic topical formulation.

500mg CBD

Each 2 oz jar is labeled as containing 500mg total CBD. This is the total CBD content of the jar—not 500mg per application.

Broad-Spectrum CBD

Broad-spectrum describes the hemp extract profile. It generally refers to CBD accompanied by additional hemp-derived compounds while being formulated to remove THC.

Camphor + Peppermint

Camphor and peppermint contribute to the balm’s distinctive topical formulation and refreshing sensory profile.

THC-Free Profile

The balm is represented as a THC-free formulation. Available lot-specific laboratory records should be used when evaluating the applicable tested product record.

Third-Party Testing

33 Supply is connecting available testing records directly to products so customers can more easily review the applicable laboratory, batch or lot, report date and original certificate.

Why 500mg Doesn’t Tell the Whole Story

The CBD market often encourages customers to compare products by milligram strength alone. But with topical products, that leaves out important information.

Two products could both contain 500mg CBD—or one could contain twice as much—and still use very different formulations, ingredients and delivery systems.

That is why we think the better way to evaluate a topical is to look at the complete product profile.

Testing and Transparency

Product education should be supported by product-specific information whenever possible.

When an applicable laboratory record is available, 33 Supply can display information such as:

• Product name
• Batch or lot
• Laboratory
• Report date
• Available analytical results
• Original Certificate of Analysis

You can review available records in the 33 Supply Lab Results & COA library.

Frequently Asked Questions

How much CBD is in the balm?

Each 2 oz jar is labeled as containing 500mg total CBD.

What makes this balm different?

The product combines a topical delivery method with a liposomal formulation, broad-spectrum CBD, camphor and peppermint.

Does a higher milligram number always mean a better topical?

Milligram strength is one product characteristic. Formulation, ingredients, delivery method, concentration and available testing are also useful factors when comparing topical CBD products.

What does liposomal mean?

Liposomal refers to a lipid-based formulation approach. Liposome-based delivery systems are studied in pharmaceutical and topical formulation science as carriers for lipophilic compounds such as CBD.

Where can I see the product testing?

Available lot-specific testing information can be viewed through the product page and the 33 Supply Lab Results & COA library.

The Bottom Line

The 33 Supply 500mg Liposomal CBD Topical Balm should not be understood solely by the number printed on the jar.

• 500mg total CBD
• Liposomal formulation
• Broad-spectrum hemp extract
• Topical delivery method
• Camphor + peppermint
• THC-free profile
• Testing transparency

Milligram strength is only one part of a topical CBD formulation.

Shop CBD Topicals   |   View Lab Results   |   More 33 Supply Articles

Research & Further Reading

The following research is provided to explain topical formulation science generally. These studies did not evaluate the specific 33 Supply 500mg Liposomal CBD Topical Balm and should not be interpreted as product-specific performance claims.

1. Casiraghi A, et al. Topical Administration of Cannabidiol: Influence of Vehicle-Related Aspects on Skin Permeation Process. PubMed.
2. Micelles-in-Liposome Systems Obtained by Proliposomal Approach for Cannabidiol Delivery: Structural Features and Skin Penetration. PubMed.